The Marshall House first opened on Broughton Street in Savannah, Georgia in 1851. However, from 1864 to 1865, it was occupied by Union troops under the leadership of General William Tecumseh Sherman and was used as a hospital for the wounded Union soldiers. It was also used as a hospital two more times during yellow fever epidemics in the 1800s, per Ghost City Tours. With such a history, it seems like it's the ideal spot for ghost hunters to visit. It became a full-time hotel again in 1999, and it's been featured on a number of haunted hotel TV shows.
On the fourth floor of the property, people have reported hearing unexplained loud noises in the middle of the night and door knobs being turned and jiggled like someone is trying to get in (via Ghost City Tours). Other guests have said they've heard children running along the halls or had faucets turned on by themselves.
If you want to amp up the spookiness during your stay in Savannah, the city has a number of ghost tours, including a tour of Bonaventure Cemetery by Dash Tours and The Restless Souls Tour by Afterlife Walking Ghost Tours that includes a stop at The Marshall House.